Useful Method to Monitor Cerebral Infarction in Atherosclerotic Patients without Atrial Fibrillation by the Combination of Carotid Intima-Media Thickness, Cardio-Ankle Vascular Index, and Plasma D-dimer

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Useful Method to Monitor Cerebral Infarction in Atherosclerotic Patients without Atrial Fibrillation by the Combination of Carotid Intima-Media Thickness, Cardio-Ankle Vascular Index, and Plasma D-dimer

Atherosclerosis: Open Access (Omics Publishing S.L) has announced almost 50 % discount on article processing charge to commemorate its 10th Anniversary.

Atherosclerosis: Open Access is an open access, peer-reviewed journal that focuses and welcomes submissions on all aspects of Coronary Heart disease, Stroke, Peripheral Arterial Disease, Chronic Kidney Disease, arteriosclerosis, Coronary Atherosclerosis, intracranial atherosclerosis etc.  

It gives us great pleasure to announce the call for paper on the occasion of 10th Anniversary of the Journal at special and hefty discount of up to 50 % on one-time article processing charge. Prospective academicians and scientists are encouraged to utilize this opportunity to get their articles reviewed, processed and published at relatively faster pace and at lower charges. In addition to this, the authors who publish with us during the year-long celebrations will also be eligible for academic awards recommended by the editorial panel.

The Archive page contains wide variety of articles such as Research / Review / Case reports / short communication / Mini review / Prospective / Letter to Editors Etc. We would like introduce a Research article which has been spread to the widest audience of experts; and thus increased in readership, citations and altimetry score.

Title: “Useful Method to Monitor Cerebral Infarction in Atherosclerotic Patients without Atrial Fibrillation by the Combination of Carotid Intima-Media Thickness, Cardio-Ankle Vascular Index, and Plasma D-dimer

Abstract: To devise an effective monitoring system for detecting cerebral infarction in severely atherosclerotic patients without atrial fibrillation. Atherosclerotic patients (284 cases; men: 97, women: 187; age: 35-96 years old; mean: 71.6 ± 10.7 years old) comprising hypertension, hyperlipidemia, lacunar infarction, ischemic heart disease, and diabetes mellitus, were enrolled and the occurrence of symptomatic cerebral infarction was observed for 40 months. They were stratified into mildly (A) (CAVI<8.0, IMT<1.1 mm) and severely (B) (CAVI>8.0, IMT>1.1 mm) atherosclerotic groups based on the level of CAVI and IMT and further divided into 2 subgroups: B, D+ (CAVI>8.0, IMT>1.1 mm, Ddimer>1.0 μg/mL) and B, D- (CAVI>8.0, IMT>1.1 mm, D-dimer<1.0 μg/mL). After 40 months, the incidence of symptomatic cerebral infarction was calculated, and analysed in the mild and severe groups and subgroups B, D+ and B, D-. The incidence of cerebral infarction in group A was 0% (0/60), while that in group B was 5.9% (5/84), showing no significance (Chi-square test). Moreover, we examined the incidence of cerebral infarction in the two subgroups, revealing that in subgroup D, B+ it was 31.3% (5/16), while that in subgroup B, D- was 0/73 (Chi-square test, p<0.0001). The rate of aspirin intake in subgroup B, D+ was 43.8% (7/16), while that in subgroup B, D- was 45.2% (33/73), suggesting that the difference in aspirin use was not significant (Chi-square test). The combination of CAVI, IMT and D-dimer was a useful tool for detecting cerebral infarction in atherosclerotic patients without atrial fibrillation. The incidence of cerebral infarction was increased in severely atherosclerotic patients with a high level of plasma D-dimer.

To have a glance at the full length manuscript, you can visit us at our archive page and Currently, Journal’s Archive is holding not only normal issues but also focusing on special issues. The purpose of special issues is to publish the most exciting research with respect to the subjects of Atherosclerosis / Cardiovascular Diseases and to provide a rapid turn-around time regarding reviewing and publishing, and to publicize the articles freely for research, teaching and reference purposes. Submit manuscript of your research articles or special issue articles online through manuscript submission or forwarded to the Editorial Office at atherosclerosis@oajournal.org

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Steven Edwards

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Atherosclerosis: Open Access

Email: atherosclerosis@oajournal.org